Shocking cat health mystery revealed: Unbelievable eosinophilia and basophilia case!"

Unveiling a Rare Feline Health Mystery: Eosinophilia and Basophilia Case

Inflammatory bowel disease can be a recurring issue in cats, marked by gastrointestinal problems and confirmed intestinal inflammation through histology. Here, we unravel a peculiar case involving a 9-month-old neutered male cat.

The Initial Presentation

This young cat was brought to our attention due to a troubling five-week history of vomiting and bloody stools (hematochezia). Initially, conservative treatment involving a special gastrointestinal diet, antibiotics, and anti-nausea medication yielded positive results. However, when the medications were stopped, the symptoms returned.

A Surprising Discovery

About three months after the initial visit, we made an unexpected discovery: the cat had significantly elevated levels of eosinophils and basophils, two types of white blood cells. A colonoscopy revealed erosions in the cecum, and a surgical biopsy confirmed a diagnosis of lymphocytic-plasmacytic and eosinophilic enterocolitis.

Treatment and Recovery

To manage this condition, we administered prednisolone, tylosin, and metronidazole to the cat. Gradually, we reduced the antibiotic dose as the cat improved. Thankfully, the cat's gastrointestinal symptoms disappeared, and the eosinophil and basophil levels returned to normal eight weeks after starting treatment.

An Unusual Combination

While eosinophilia has been linked to feline T-cell lymphoma, marked basophilia alongside eosinophilia is exceptionally rare in cats with inflammatory bowel disease. This case emphasizes the importance of considering enteritis as a potential diagnosis when cats exhibit both eosinophilia and basophilia.

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Case report: Lymphocytic-plasmacytic and eosinophilic enterocolitis presented with marked eosinophilia and basophilia in a cat